Philadelphia (tca/dpa) — Drinking alcohol in moderation is generally defined as having one drink a day for women, two for men. But even those modest-sounding amounts may have negative impacts on the brain, a new study led by University of Pennsylvania researchers suggests. People who drank the equivalent of just one daily glass of wine — or one can of a higher-potency beer such as India pale ale — were found to have slightly smaller brains, on average, than nondrinkers. The apparent effect from one daily drink was equivalent to two additional years of brain ageing for a typical 50-year-old, th…