By Kevin McGuire Here are the 11 toughest college football players that Big Ten teams will have to replace in 2022. The 2022 NFL Draft is setting up to be flooded with terrific talent out of the Big Ten, led by some of the usual names when it comes to the NFL draft. Ohio State, Michigan, and Penn State are all about to send off some big-time players to the next level, but some of the best draft picks may be coming out of Iowa or Purdue as well. Related: 10 Big Ten Players Who Will Replace NFL Draft Early Entrants in 2022 And in what is looking to be a unique year with the draft and players ret…