By Alek Arend Deebo Samuel appears to be incredibly frustrated with the San Francisco 49ers. Samuel has made several big changes to his Instagram profile. Most notably, he’s removed his profile picture and most of his posts that featured anything 49ers-related. This all stems from Samuel’s desire for a new contract. He’s still playing on his rookie contract. However, you could argue he’s currently a top-five wide receiver in the NFL. It appears John Lynch and Co. are taking too long for Samuel’s liking. They better hurry. Losing Samuel would be detrimental. These aren’t the only changes Deebo …